The summary statistics of human TFBS predictions according to both the Poscons and the Turnover methods are given in Tables 1 and 2. A column in a PWM is a probability distribution of the 4 nucleotide bases, A, C, T and G. Information content (IC) of a PWM column measures its specificity[18].
Moreover, across chronosere species turnover (see methods) for lizards is significantly higher than that for frogs (Student's t-test, two tail p < 0.05), indicating that lizard community succession was characterized by relatively high replacement and low accumulation of species.
Employing single-turnover kinetic methods, we examined human DNA polymerase β and its novel X-family homolog, human DNA polymerase λ, to determine which nucleotide and template base was preferred when encountering 8-oxodG and 8-oxodGTP, respectively.
To directly test this possibility, postdoc Roger Deal introduced the CATCH-IT (Covalent Attachment of Tags to Capture Histones and Identify Turnover) metabolic labeling method for measuring nucleosome turnover (Deal et al. 2010).
Most importantly, these results reveal the potential of rate heterogeneity among lineages to severely bias some turnover rate estimation methods and the need of further evaluating the performance of these methods in a more diverse sampling of gene families and phylogenetic contexts.
Furthermore, to assess fiber type-specific absolute total and phosphorylated concentrations of the major signaling molecules involved in muscle protein turnover, quantitative immunohistological methods or in situ hybridizations (van Beek-Harmsen et al. 2004; van Beek-Harmsen and van der Laarse 2005) are required.
Their capability of catalytic degradation of formaldehyde solution with oxygen air bubbles were studied by using an acetylacetone calorimetric spectra, total organic carbon (TOC) method and turnover number (TON).
This novel method of turnover analysis does, however, have several limitations.
Nitrogen (N) metabolism and whole-body protein turnover were measured by classical method and single-dose 15N end-product method, respectively.
