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A mathematical analysis of the impact of the different model parameters on the so-called mechanobiological stability margin, a single scalar used to characterize mechanobiological stability, reveals that this stability increases with the characteristic time constant of mass turnover, material stiffness, and capacity for stress-dependent changes in mass production.
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All these outlets demand a huge turnover of material, and the most obvious target for a desperate sketch-writer is politics.So far, the Blair team's occasional fumblings are as nothing to the farce seen in the final days of John Major's Conservative administration.
Dnm1-GFP levels are relatively stable over a 24 h period with little change in turnover (Supplementary Material, Fig. S4B).
This indicates that at this point in the life cycle of P. polycephalum, the normal turnover of material can take place and this might be responsible for its ability to resume growth instead of committing to spherulation or sporulation.
We cannot distinguish whether the accumulation of autophagic organelles reflects a decrease in the efficacy of turnover of materials by the autophagosomal pathway, or whether the pathway is being overwhelmed by an increase in the bulk of material that enters it.
I checked its investment policy (you want the "stewardship" pdf) and noticed they don't allow investment in companies that derive material turnover or profit from tobacco or tobacco-related products.
It is conceivable that higher turnover of faecal material influences community dynamics.
The resulting products are then available for recycling in biosynthetic pathways; thus autophagy is one of the main lysosomal pathways for biological material turnover.
The large-scale turnover of intracellular material including organelles is achieved by autophagy-mediated degradation in lysosomes.
Following is the mathematical equation for this reaction kinetics to describe HIF1α turnover (see Supplementary Material for details): 3Initial condition: 4HIF1α0 is the baseline HIF1α level.
To assess the effectiveness of this exercise, we asked students (n = 18) in our summer cell biology class to complete an assessment form composed of nine questions after completing this membrane turnover exercise (Supplemental Material 3).
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Justyna Jupowicz-Kozak
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