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The decrease in epidermal cell turnover is accompanied by an increased expression of products of keratinocyte differentiation, especially K1 and loricrin (Figure S1).
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Both in CNF and FSGS kidneys, deregulations of cell turnover were accompanied by apoptosis of tubular and mesenchymal cells, as also described in human kidney malformations associated with urinary tract obstruction [ 14].
For example, it is well known that PAH is accompanied by the turnover of extracellular matrix constituents, including hyaluronic acid [18].
This is accompanied by high turnover.
PPARα activation is accompanied by increased hepatic lipid turnover via the β-oxidation system, which reduces lipid accumulation that can result in hepatic toxicity (Harano et al. 2006).
The flexibility hypothesis implies that thermal adaptation of enzymes is accompanied by shifts in catalytic turnover numbers (kcat) and catalytic efficiency (kcat/Km).
In general, scarring is accompanied by a lower MMP to TIMP expression ratio, as a slow collagen turnover leads to increased protein accumulation.
Swelling is accompanied by stiffness.
All measurements of turnover frequency were accompanied by one or more selectivity data.
We hypothesized that if bone marrow lesions are areas of accelerated bone turnover, then they should be accompanied by elevation in systemic levels of bone turnover markers.
Biodegradation was accompanied with a turnover of glucose intermediate and a production of lactic acid.
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