Exact(2)
Blocking MVB turnover enhanced, whereas blocking MVB maturation inhibited miRNA-mediated target mRNA silencing, indicating that MVBs and GW bodies are functionally involved in miRNA-mediated RNA silencing.
At 10 μg/ml all drugs induced increased lysosomal activity (LTR), with digoxin additionally upregulating endolysosomal turnover (enhanced loss of GFP-Rab7 fluorescence).
Similar(58)
For example, mentoring programs can help the organization by attracting talented employees who see mentoring programs as evidence of the organization's commitment to employee development, reducing individual employee turnover, enhancing employee productivity, and increasing the retention of women and minorities.
Because osteoclastic bone resorption and high bone turnover enhance tumor growth in bone [10], [11], we hypothesized that Arf loss in Tax mice would accelerate the growth and progression of tumors in the bone.
In transgenic glands, before lesion development, epithelial cell turnover was enhanced overall compared with nontransgenic glands, indicating that aberrant cell turnover in normal epithelia may contribute to tumorigenesis.
The increase in autophagic turnover could enhance mitochondrial turnover and biogenesis, and, consequently, decrease ROS production.
It might be due to a reduction of Sec31 and Sec23 turnover in the absence of other COPII components, perhaps suggesting that Sec31 and Sec23 turnover is enhanced by COPII coat formation.
Similarly, collagen turnover is enhanced in sepsis, and this is reflected in elevated levels of circulating collagen degradation products [19].
The bone turnover was enhanced in bone metastatic patients, in particular we observed both an increase in bone formation and resorption markers.
In chase experiments, expression of ERβ1 reduced the half-life of EGFR suggesting that EGFR protein turnover was enhanced by ERβ1.
Assuming that the overall protein turnover rate is enhanced, an absence of enhanced protein synthesis rate will result in net protein breakdown leading to net protein loss.
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