Dynamic actin turnover is critical to the health of neurons due to its role in maintaining the plasticity of dendritic spines, which is critical in projection neurons (31).
Identifying and understanding the active sites responsible for reaction turnover is critical to developing improved catalysts.
Understanding the source of soil organic carbon (SOC) in deep soil horizons and the processes influencing its turnover is critical for predicting the response of this large reservoir of terrestrial C to environmental change and potential feedbacks to climate.
Employees who feel recognized for their work are also more likely to stay with a company, resulting in less turnover, a critical factor for your bottom line.
Engaging a diverse set of stakeholders is imperative for ensuring that the program meets the needs and interests of those who stand to benefit, namely the elementary teachers and students, but also to sustain the program despite turnover among critical individuals.
Because actin turnover is critical for maintaining AJC [35], thus Cofilin 1 may be required for the E-cadherin-mediated adhesion of EVL/DEL.
A highly regulated cell turnover is critical in maintaining the secretory properties of the terminally differentiated lactating mammary epithelium.
Furthermore, nucleocytoplasmic shuttling of PER proteins, in conjunction with protein dimerization, phosphorylation and turnover, is critical for clock function (Yagita et al., 2000, 2002).
Therefore, rapid FA turnover is critical for cells to become motile, while cells with more stable FA are generally less motile and thereby less invasive (Mitra et al, 2005; Xu et al, 2009; Xu et al, 2010).
Its role in protein turnover is critical for optimal cell performance, as a decrease in proteasome activity has been shown to lead to an accumulation of protein aggregates and overall cellular dysfunction (Wong & Cuervo, 2010).
