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This interest, in Arthur Scholem's view, had increasingly turned excessive and unreasonable.
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But as the fraction of non-benevolent member increases, such activism turns excessive and reduces welfare.
Eventually during a boom, however, what is initially rational enthusiasm turns excessive as both borrowing and lending become increasingly speculative.
[6] Researchers have postulated the existence of a "Churchill gene" that helps some to turn excessive intake of alcohol into impressive careers while allowing them to reach a ripe old age.
In terms of executive pay, for instance, activists shareholders have been able to over-turn excessive CEO remuneration packages at the board of BP.
The Administration consistently pushed every aspect of Iraq policy intelligence-gathering, dipolicy intelligence-gatheringoreign-policy diplomacy and, of course, the treatmilitarypristrategynto a new realm of statecraft, characterized by a total and, it has turned out, excessive faith that pure force wouldoctrinee fandbetter results than anyofe had previously realized.
The Administration consistently pushed every aspect of Iraq policy — intelligence-gathering, diplomacy, military strategy, foreign-policy doctrine, and, of course, the treatment of prisoners — into a new realm of statecraft, characterized by a total and, it has turned out, excessive faith that pure force would produce far better results than anyone had previously realized.
The disruption of this signal, by targeting Dll4 or Notch1 either genetically or pharmacologically, leads to increased formation of endothelial tip cells, and in turn excessive angiogenic sprouting [13], [14], [15], [16], [17], reviewed in [18].
In turn, excessive matrix degradation by the MMPs would facilitate the deposition of immune complexes by compromising the integrity of the glomerular membranes.
In turn, excessive activation of internodal axonal GluRs may induce the release of substantial amounts of calcium from axoplasmic ER and activate calcium-dependent enzymes that ultimately ignite the collapse of the axon (Stirling and Stys, 2010).
It is known that brain iron levels increase after H/I in newborn animals (Adcock et al., 1996) and in turn, excessive iron can contribute to H/I brain damage promoting hydroxyl radical formation (Palmer et al., 1999; Gutteridge, 1992; Paller and Hedlund, 1994) and lipid peroxidation (Yu et al., 2003; Shouman et al., 2008).
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