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Thus, it seems that 5-HT in the periphery provokes a release of dopamine, which in turn targets D1 receptors, thus causing a nociceptive response.
This phosphorylation leads to the recruitment of arrestin, which, in turn, targets the GPCR to the clathrin-coated pits.
This in turn targets other proteins for tagging with ubiquitin, which marks the protein for destruction.
This is because SPL, the target of miR156, is an elicitor of miR172 promoter region which, in turn, targets APETALA2.
Ras activates the MAP kinase pathway, which in turn targets nuclear transcription factors promoting mitogenesis (Shaw and Cantley, 2006).
SHP also activates miR-206 expression through a "dual inhibitory" mechanism [ 81], which in turn targets Notch3 for degradation [ 82].
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This giant virus is in turn, targeted by an infectious virophage (Sputnik 2), which is then further infected by transpovirons (bits of parasitic DNA) [124].
Erosional and depositional processes control the preservation and occurrence of specific regolith units that may be used as sample media and, in turn, target size, element associations and contrast, thereby influencing sampling procedures, analysis and data interpretation.
Many of the Hutus who fled were then, in turn, targeted by DRC militias, including M23, a militia backed until 2013 by Kagame's government.
Importantly, miR-24-2 can in turn target the 3'-UTRs of Interferon γ, JUN, and FOS genes (Figure 5Bii) and therefore potentially inhibit the mRNA expression levels of these genes.
The latter, in turn, targeted several markers of EMT, including ZEB1 and vimentin.
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