At least for some reporting items the need to ensure reliability of information may result in delayed publication, which in turn reduces relevance (see, e.g., Alexander and Nobes 2013, p. 43).
Considered and meticulous outcome measurement is central to rigorously conducted effectiveness trials, and in turn the relevance and reliability of the study findings to the patient, therapist or policy maker.
However, it is tempting to speculate that in humans (1) the degree of biological impact of somatic POLE aberrations on protein function and in turn clinical relevance appear to be cancer-specific rather than of general and equal importance and (2) a somatic mutation in one allele of POLE per se may not necessarily be sufficient to yield a specific clinically distinguishable phenotype.
Justice Scalia in turn disputed the relevance of that fact.
This made for an especially lively campaign, and in turn diminished the relevance of the government-friendly media.
Thus, such programs can potentially bridge the opportunity gap that low-income youth face by providing enriched engagement and in turn increase the relevance of STEM learning (Afterschool Alliance 2011; Ejiwale, 2013).
Finally, as emphasized above, a concern with the pragmatics of explanation, naturally connects with an interest in the "psychology" of explanation, and this in turn suggests the relevance of empirical studies of sorts of information that various subjects (ordinary folks, scientists) find explanatory, treat as providing "understanding", the distinctions subjects make among explanations and so on.
This, in turn, reinforces the relevance of the KB program.
Over time, patients necessarily come to terms with this situation, which in turn lessens the relevance of the health impairment.
