Exact(14)
In turn, activation of the mitogen-activated protein kinase pathway has been shown to play a role in vascular smooth muscle proliferation.
NO in turn activates sGC leading to a rise in intracellular cGMP and, in turn, activation of cGMP-dependent PKG, or cGK [54, 55].
The two last effects but not the first one were blocked by CGP55845, indicating that GAT-1 blockade causes an elevation of extracellular GABA concentration and in turn activation of extrasynaptic GABAARs and presynaptic GABABRs.
In turn, activation of AMPK can stimulate HO-1 expression and thereby attenuate cytokine-mediated cell death [55].
Stimulation of PAC1 receptor causes in turn activation of the cyclic adenosine monophosphate/protein kinase A pathway leading to the opening of adenosine triphosphate sensitive potassium channels [56].
Defective lysosomal degradation of GM1 was found to provoke the redistribution of this ganglioside at the ER membranes, where it induces depletion of ER Ca2+ stores, and in turn activation of the unfolded protein response (UPR) and UPR-mediated apoptosis [11].
Similar(46)
RAF activation in turn activates the serine/threonine kinases MEK1 and MEK2, which in turn activate ERK.
Th1 CD4+ T-helper cells also enhance antitumor immune responses by secretion of INFγ, which in turn induces activation of macrophage cytotoxic activity [ 58].
In turn, continuous activation of ARRs arrests meristem activity and WUS expression, suggesting that WUS and ARRs mutually repress each other.
When substrates forming the interface are adhesive, the transmission of shear is delayed, in turn delaying activation of mechanophores.
In turn, the activation of such pre- or extra-synaptic NR2B-containing NMDARs can modulate the threshold of the induction of Long Term Potentiation.
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