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Match-3 is great for this because it's more of a compulsive mechanic that feels very natural and tuning level difficulty is a little more straightforward.
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Xiong, X. et al. The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein.
On a fine-tune level, the gene encoding the alpha-subunit of the Integration Host Factor (IHF) and hutC, which both control transcription of the virB operon via specific promoter binding sites, were also up-regulated under nutrient stress conditions.
Together, these results suggest that precisely tuned levels of FimL are critical to modulate cAMP levels.
This discovery led to the hypothesis that Int6 can fine-tune levels of key regulatory proteins by coordinating protein synthesis and protein degradation within the translasome.
A similar small magnitude of change in MeCP2 target genes was also detected using ISH studies (39, 40); suggesting that MeCP2 modulates gene expression and fine-tunes levels of its target genes rather than causing large fold changes.
This paper presents a performance-based railway timetabling framework integrating timetable construction and evaluation on three levels: microscopic, macroscopic, and a corridor fine-tuning level, where each performance indicator is optimized or evaluated at the appropriate level.
Cross-activation or cross-talk between the modules, however, will restrict the fine-tuning level of the flux distribution.
Tuning this level without affecting the high-end saturation level is equivalent to tuning both k′ and k, while keeping their sum k′ + k constant.
This model introduces a parameter, e, that allows for tuning the level of fractality in the network.
This work demonstrates a good example for tuning energy level and photovoltaic properties of the polymers by the application of 2D conjugated structure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com