In this way, the ability of KLK6 to regulate survival of T and B cells would be sharply tuned by differential expression of receptors activated by KLK6 in response to changing environmental cues.
TEV protease could then be added to the collagen gel matrix, where the cells are grown, in order to tune this differential degradation function.
The new formulas for the tuning parameters of Differential Evolutionary technique are designed in such a manner that they become automatically adaptive throughout the whole iteration.
In mammals, chicken, and frogs, this "differential tuning hypothesis" was supported by careful comparison of the evolutionary patterns between the two types of chemosensory receptor gene families [11].
For example, neurons in the hand area of the primary motor cortex show a differential tuning for different finger movements of the contralateral hand.
Since voxels in M1 are known to show differential tuning for isolated finger movements (Diedrichsen et al., 2013b), some voxels may show higher activity early in each sequence, while others would peak late in the sequence.
In root apices, drought-driven regulation was highly consistent in both genotypes, and it was the differential tuning across drought conditions that accounted specifically for the loss of conservation in gene co-expression relationships.
DOI: http://dx.doi.org/10.7554/eLife.03043.017 Our study employed fMRI multivoxel pattern analysis that reflects the differential tuning of individual voxels (Kamitani and Tong, 2005; Kriegeskorte et al., 2006) to identify neural representations of spatial and temporal finger sequence features.
Ultimately we cannot tell from our data whether the emerging diversity and clustering of electrophysiological properties at stages 48-49 is due to differential tuning with a single cell type (sometimes referred to as "neuronal subtypes" (McGarry et al., 2010), or a sign of emergent cell differentiation that would only become obvious at post-metamorphic stages.
The superiority of the proposed approach is shown by comparing the result with output feedback tuned SMC with differential evolution and particle swarm optimization and state feedback SMC tuned with genetic algorithm for a two area thermal interconnected power system.
The spectral viscosity method is applied for this purpose, and we discuss implementation aspects, effects on the resulting system of ordinary differential equations, tuning of parameters, and evaluation of results.
