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These results suggest a specific mechanism, removal of TEs, by which highly expressed genes are selectively tuned for efficiency.
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One is tuned for energy efficiency -- for Web surfing or reading e-mail messages -- and the other is for high-performance, graphics-intensive applications like editing video or playing games.
Linear-time algorithms for suffix array construction have been proposed as well as algorithms that are fast in practice and/or tuned for space efficiency, rendering use of suffix arrays feasible for large datasets; see Puglisi et al. (2007) for a comprehensive overview.
Our results illustrate that the evaluation metrics used to rate these heuristics in previous work were not tuned for bug-finding efficiency, which we believe is the major criterion that the heuristics need to meet.
Four hybrid detectors (HyD) were spectrally tuned for optimal detection efficiency and low bleed through of signal: second harmonic generation of collagen (HyD1: 400–425 nm), autofluorescence of adipocytes and GR1/eFluor450 (HyD2: 445–500 nm), autofluorescence of adipocytes/elastin, and CD115/Alexa488 (HyD3: 515–555 nm) CD45/nanocrystal-605 nm (HyD4: 590–625 nm).
"We have some details to work out in that part… This business has been tuned for growth, not necessarily for efficiency".
According to a Toyota spokeswoman the Prius goes from zero to 60 miles per hour in 10.1 seconds, but could go faster if, like the Lexus hybrid, it were tuned for performance rather than efficiency.
The engine design, using cylinder heads with hemispherical combustion chambers to improve efficiency, was not new to Chrysler, but had never been tuned for such high output.
Stay tuned for 2012.
Stay tuned for that!
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