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Tests are also made to estimate maximal tubular activity, tubular mass, and tubular function.
The action of aldosterone has been described as priming the sodium reabsorption pump; it is the adrenal hormone most important to tubular function.
The β2-MG concentration is mainly related to renal tubular function.
Diuresis, a marker of both GFR and tubular function, was measured at each time except T30.
They found that 3%% had abnormal glomerular function while 51%% had impaired tubular function.
Loop diuretics gain access to tubular lumen through active secretion, and their action is therefore dependent of tubular function [48].
Nevertheless, also an increased excretion of the low molecular weight protein RBP represents an impairment of renal (tubular) function.
Notable exceptions to this interpretation include conditions which interfere with normal tubular function with the most prominent examples being the use of thiazide diuretics and severe kidney disease.
This protein has an immunomodulatory role, with a broad spectrum of possible clinical applications, besides being a promising marker for evaluation of tubular function [33].
The nephrotoxicity of AMB has been manifested by renal insufficiency due to vascular and glomerular disease besides the abnormality in tubular function.
The PDNO-treated sheep displayed a significantly lower ratio between consumed oxygen and reabsorbed sodium, perhaps indicating less ischemic injury to tubular function.
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