Sentence examples for tuberculosis development from inspiring English sources

However, a significant trend for tuberculosis development amongst high HHC IFNγ producers was observed (trend Log rank p = 0.007).

Herein we present evidence that levels of IFNγ response to CFP-10 assessed shortly after exposure to an infectious source may be predictive of tuberculosis development in a population of HHCs at high risk of infection.

Given the very high rates of tuberculosis development observed in children and the fact that we could not offer them IPT, as recommended by several international guidelines [29] [31], the ethical implications of this study is a highly relevant issue.

We estimated the prevalence of M. tuberculosis infection by IGRA and TST in HHCs and their source population (SP), and assessed whether IFNγ levels in HHCs correlate with tuberculosis development.

Taken together our results clearly demonstrate that HHCs are a population at high risk of infection and disease development and show a marked difference in the risk of tuberculosis development depending on the levels of IFNγ production in response to CFP-10 shortly after exposure to M. tuberculosis.

However, some genes with influence on tuberculosis development are well investigated and confirmed.

Various risk factors for tuberculosis (TB) development have been identified.

This review summarizes recent advances in tuberculosis vaccine development.

Macrophages are involved in a number of diseases, such as HIV infection/AIDS, tuberculosis, tumor development and atherosclerosis.

Understanding the phenomenon of persistence is therefore one of the priorities in tuberculosis drug development programs.

This is relevant information for approaches that study bacillary characteristics in pooled samples (using lipidomics and proteomics) as well as in M. tuberculosis drug development.