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Synaptic release in MB neurons of adult flies was inhibited by expression of a temperature sensitive dominant negative dynamin transgene (UAS-Shi ts ) under control of either mb186bGAL4 or mb247GAL4 drivers.
The CFN was played from a CD player and superimposed on the TS under control of the audiometer.
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Mice overexpressing the polyoma virus middle T under control of the MMTV promoter (PyMT) were purchased from Jackson Laboratories (Bar Harbor, Maine).
To silence mushroom body neurons, we expressed Shi ts under the control of 5-120 GAL4, which drives GAL4 expression broadly in all lobes of the mushroom body (Joseph et al. 2009; Kaun et al. 2011).
The effect of both buffers on CDI and, thus, on ICa, CICR, and the Ca2+ transient is greater at the t-tubular dyad than at the surface dyad, because of the more marked CDI at the t-tubules under control conditions.
The results, Reisner says, suggest that the normal role of the perforin-positive dendritic cells is to keep certain populations of T cells under control.
This transgenic tumor model carries the SV40 T antigens under control of the rat insulin promoter, which is expressed in the islets of Langerhans in the pancreas.
As Tregs can keep effector T cells under control, they likely inhibit FIX-specific Th in the treated mice.
For this purpose, we used the MMTV-PyMT murine model whose oncogenesis is induced by expression of the polyoma virus middle T oncoprotein under control of the Mouse Mammary Tumour Virus (MMTV) promoter (PMID: 1312220).
Interestingly, IFNγ-RGR predominantly acted as an anti-vascular agent in RIP1-Tag5 transgenic mice, which express the SV40 Large T antigen under control of the rat insulin gene promoter and develop pancreatic neuroendocrine tumors over time.
The standard approach for implementing a specific quantum gate (hat {mathbf {O}}) using optimal control theory is to maximize the overlap between the time evolution (hat {mathbf {U}}(T,0 epsilon(t))) under the control (epsilon(t)) and the target gate [19].
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