This somatic mutation in an Apc allele, which leads to a truncated Apc protein, causes the development of adenomas in the distal colon as early as 10 weeks.
In Hydractinia, gonophore development is greatly truncated and never reaches the medusae stage.
Moreover, MtErf1 seemed to be required for arbuscule development, since only truncated, non-fully branched arbuscules were present in roots with amiR-silenced MtErf1 expression.
Others utilized a transgenic mouse model with known modifications to the collagen type II gene that result in the development of a truncated collagen fiber.
This has been used to both knock down DISC1 expression and to overexpress normal or truncated DISC1 during early CNS development (Kamiya et al., 2005; Meyer & Morris, 2009; Kubo et al., 2010; Niwa et al., 2010; Tomita et al., 2011; Maher & LoTurco, 2012).
New developments also include truncated pores, which pierce bilayers through lipid rearrangement, and hybrid pores, which do away with bilayers altogether.
One of the stars of the beloved "Arrested Development," cancelled after a truncated third season by Fox after a long series of near-executions, Arnett's admittedly less renowned second series, "Running Wilde," got the axe by the same network before it could even reach the middle of its first season.
Transgenic expression of a truncated p100 protein led to the development of B-cell lymphomas in mice, thus demonstrating the oncogenic potential of Nfkb2 mutations [18].
"The network television development model has a very truncated period in which pilots can be developed and produced," he adds.
The antiviral activity of LL-37 is retained by a truncated peptide fragment, which opens the possibility of development of shorter peptide analogs, which may enable development of newer therapeutic interventions for RSV.
