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Because cse4-1 is a hypomorphic mutation [26], CEN4 binding by Spc105p/Kre28p in cse4-1 cells does not demonstrate that centromeric chromatin is truly dispensable, but it does distinguish the Spc105p/Kre28p complex from COMA and MIND.
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A sign of a truly great leader is to become dispensable, to teach the people how to lead themselves.
Except looking for someone dispensable would not really be sensible at all.
This is expected because the dispensable part of the genome may be partly shared among different cultivars and only a few genes may be truly unique to a particular accession [ 15].
Dispensable ghosts?
Monty Panesar looks dispensable.
Art is dispensable.
His parents are dispensable.
"Black children are dispensable.
Flint is dispensable.
We are cheap and dispensable.
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