Sentence examples for true linkage from inspiring English sources

First, there may be no true linkage for these disorders.

Consistent evidence of linkage across multiple methods increases support for a true linkage.

These may be due to chance findings in one analysis, or they may be true linkage that only one method was sufficiently powered to detect.

If disease risk is largely mediated by rare or private causative variants, then individual linkage studies and conservative meta-analytic approaches may fail to produce findings exceeding standard significance thresholds, even in the presence of substantial heritability and true linkage [4].

In this way the detection of true linkage disequilibrium is favored versus just family linkage.

Also note that the independently generated variants do not reflect the true linkage disequilibrium pattern of the human genome.

This assumption serves to inflate apparent values of r, increasing the likelihood of detecting true linkage-disequilibrium (at the cost of an increased false positive rate).

Imperfect tracing and the tendency for adults in this setting to change their names to ensure anonymity in HIV clinics likely resulted in underestimates of true linkage-to-care rates.

Importantly, simulation studies indicate that although allele frequency misspecification can lead to false positives, this artefact is not expected to affect the power to detect true linkages.

The percentage of true linkages between consecutive heterozygous markers that differed from estimated linkages was determined, as well as the percentage of heterozygous loci at which the allele estimated to be paternal was actually maternally inherited.

There are four possible outcomes from record linkage: true matches (true positives), true non-matches (true negatives), mismatches (false positives) and false non-matches (false negatives) [ 44].