Sentence examples for true impairment from inspiring English sources

To determine whether premature ovarian insufficiency (POI) associated with classic galactosemia results from a true impairment of ovarian function or from aberrant FSH.

Thus, it is feasible that caloric restriction during gestation could lead to partial noradrenergic dennervation of the inguinal adipose tissue and therefore favour the hyperplasia seen in this fat depot in adulthood; however more functional studies could be performed to fully demonstrate a true impairment in sympathetic regulation.

In general, a low prevalence or base rate of true cognitive impairment in a particular setting tends to reduce the positive predictive value or the probablility that a positive test represents true impairment while false negatives will remain low.

For example, using a less stringent criterion for impairment [e.g., the 25th percentile (z-score ≤ −0.67)] indeed increases the identification of true impairment (increased sensitivity), but it is also associated with reduced specificity (i.e., the percentage of healthy individuals erroneously being classified as impaired is high; see Fig.  1) [ 12].

If this converging evidence from both structural and functional neuroimaging and computational modelling in favour of a dual stream segregation for language processing holds true, impairments of repetition and comprehension in patients with acute aphasia should correlate with lesions of either the dorsal or ventral stream.

The assumption made here is that the bits of each component define a real number (or set of real numbers) and that the true RF impairment is a continuous function of this (set of) real numbers.

In contrast, when the base rates of true cognitive impairment are high, the positive predictive value is high but there is an increased probability that a negative test will not reflect a true absence of impairment.

However, given that healthy older adults may also show a gradual but clinically insignificant cognitive decline over time [ 10, 11], these cognitive changes may be very subtle, such that in clinical practice detecting true cognitive impairment remains challenging [ 8].

Finally, although mortality was similar across most variables with missing data, this was not true of driver impairment where drivers with missing information tended to be driving older passengers.

30 This is particularly true with visual impairment, since daily tasks require a great deal of concentration and effort.

It is reasonable to assume that a patient's true underlying cognitive impairment progresses linearly over short follow-up durations that are typically considered in clinical trials.