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This is a statistical effect only in the sense that a "true" dataset is filtered due to a detectability threshold.
In order to evaluate how well the subset represents the global distribution of the whole dataset, we use the distance metric: Kullback Leibler (KL) divergence between the distribution of the fake dataset reconstructed from the subset and the distribution of the true dataset.
As expected, PARADIGM converged much more quickly on the true dataset relative to the null.
The intention of their taxonomy however is to evaluate genefinder accuracy versus a known true dataset and to measure the effect of modifications to genefinding software [ 8].
We defined the chimerity used to detect CF by using trio-based haplotypes in our previous research and use this indicator to define the true dataset.
Only uniquely classified reads from the true dataset and suspected false positives from the synthetic dataset were verified with MEGABLAST due to the slow processing of this algorithm, making it a very time-consuming task to verify all classified sequences.
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The algorithm iteratively maintains and adapts an approximating distribution to the true datasets per the difference between the approximating datasets and the true datasets used as the multiplicative weights for updating.
The true positive dataset is the experimentally annotated dataset of SLiM domain interaction interfaces (SLiMDoM dataset) based on the aforementioned literature survey and the crystal structures retrieved from the 3DID database.
Therefore, the EOF series in Eq. (2) converges most quickly in representing the true height dataset.
Until now, such a true negative dataset for chemical entity mentions was missing.
This smaller subset can be used as a true negative dataset of abstracts that do not mention SACEMs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com