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Most of the studies also were observational, meaning that patients completed questionnaires about their activities, which can be unreliable since people may not accurately recall their true activity levels.
In general, the PSF correction overestimated the true activity concentrations.
When vials were surrounded by water, measured activity was almost equal to true activity (−0.02%).
Resulting TACs were compared with the true activity concentration both before and after implementation of IDM.
The true activity distribution is represented with the same voxel size than the reconstructions.
In clinical studies, true activity concentrations and distributions within the brain are not known.
SUV50 underestimated the true activity concentration and SUVmax overestimated the values (Table 4).
All average measurements of total activity were within ± 10% of true activity for activities ≥ 0.5 GBq.
We placed a uniform amount of activity in the liver compartment representing a true activity distribution.
RCs are defined as the ratio of the measured activity concentration to true activity concentration.
Figure 3a shows the measured activity versus true activity within the whole FOV along the identity line, averaged across the eight sites, and Fig. 3b shows the percent differences in total measured activity and true activity.
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