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Release at or close to the trough temperature of entrainment consistently resulted in phase advances.
The lowest (trough) temperature achieved during each cryoballoon application was recorded.
Two 5 min cryoballoon applications were applied to each PV, aiming for a trough temperature of less than −40°C.
Behavioral phase advances were observed upon release at constant trough temperature even for mutants that block per splicing (see Additional file 6).
Moreover, this relationship is relatively insensitive to changes in the time of trough temperature or other features of the temperature profile (see Figure 2B and 2C).
In all PVs except the left upper pulmonary vein (LUPV), PV isolation was associated with lower mean trough temperature achieved during balloon cryotherapy (table 3).
Similar(52)
The behavioral phases of flies released at peak versus trough temperatures showed non-overlapping distributions with a highly significant difference (t-test P < 10-6).
Additionally, the frequency of temperature measurements in our study varied significantly, which made it difficult to ensure that peak and trough temperatures and acute changes in pattern were fully appreciated in every patient.
Samples with increasing nitrogen contents at the surface were obtained trough high temperature gas nitriding.
The operal conditions for each stage were: pressure 56 bar, LHSV 1.65 H2/HCH2/HC ratio 56 m3/Bl (hydrogen flow was once trough) and temperatures in the range of 613 653 K.
Equatorial Ionization Anomaly (EIA) observed in electron density, morning and afternoon enhancements, equatorial trough in electron temperature have been simulated by the model within reasonable limits of accuracy besides reproducing other normal diurnal features of density and temperature.
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