Sentence examples for troublesome sequence from inspiring English sources

Although this technique was employed by the Curies to isolate radium it never became widely used because it entailed a lengthy and troublesome sequence of operations: partial freezing, separation of the crystals from the unfrozen liquid, remelting, and recombining with other fractions.

By virtue of their low copy number, fosmids often mitigate problems with the cloning of troublesome sequences.

I'm speaking of the notoriously troublesome "Salic law" sequence at the start of Shakespeare's "Henry V".

A large majority of juxtacentromeric regions have been left out from the genome sequencing project as segmental duplications made clone assembly and sequencing troublesome in these chromosome regions.

However, it inevitably depends on alignments of sequences, which is potentially error-prone and troublesome especially for distantly related sequences.

This finding indicates that the BLSOM can be used for protein function estimation that does not rely on sequence homology searching and troublesome and confusing sequence alignment.

Lines with highly heterozygous regions are potentially more troublesome, because loss of heterozygosity between sequencing and phenotyping cannot be ruled out without additional analysis.

This compounds with difficulty in identifying homology by sequence alignment [ 29], the troublesome task of assigning orthologous relationships [ 28], and the problem of saturation of substitutions [ 15].

They begin to become obsessed with theses dreams and desires, which take on a troublesome aspect; inventively staged, slickly executed movement sequences show the two men doing battle with very modern anxieties and fears.

One set of troublesome ORFs identified during PCR and confirmed during sequencing revealed duplication of either the 5' (near the ATG) or 3' (near the stop codon) sequences used to design the PCR primer elsewhere in the clone.

Different strategies and parameter combinations were tested and their impact on the results was evaluated, since we observed that the systematic comparison of short DNA sequences, such as cis-elements, was troublesome [ 73].