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The first trophic factor, a protein called nerve growth factor, or N.G.F., was discovered in Dr. Hamburger's laboratory.
PGD2 acts as a neuromodulator and a trophic factor in the central nervous system.
However, chronic trophic factor delivery prohibits dose adjustment or cessation if side effects develop.
Secretion of an endogenous trophic factor, VEGF, was increased ∼5-fold.
Glial-derived neurotrophic factor (GDNF) is a trophic factor for the nigra-striatal tract in experimental Parkinson's disease (PD).
Several lines of evidence indicate that Glial cell line-derived neurotrophic factor (GDNF) is a trophic factor for dopaminergic neurons.
Transferrin is a key myoblast trophic factor, initially promoting myoblast proliferation and subsequently supporting myogenic differentiation.
Something similar occurred with cell adhesion molecule L1-CAM and trophic factor GDNF.
We examined whether or not the OE could release soluble trophic factor(s) by testing OE conditioned medium (OECM).
The rise in oligodendrocytes observed may hence be due increased need for myelination and trophic factor support.
This gene is expressed by astrocytes where it acts as a potent trophic factor for neurons [36].
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