Molecular weight discrepancies between endogenous ADAMTS-12 protein species in EVTs and first trimester placenta (35 kDa major product) compared to exogenous ADAMTS-12 in JEG-3 cells (83 kDa major product) were observed.
The main rationale of routine histopathologic examination of products after first-trimester miscarriages is to detect an ectopic pregnancy or a molar pregnancy, which require further management.
The authors of these studies concluded that routine histopathologic assessment of products of first-trimester spontaneous miscarriage canlead to the diagnosis of important pathologies, more effectively identify ectopic pregnancies or infections than clinical or other laboratory criteria, and may reduce mortality.
Objective: To evaluate the value of histopathological examination of products of conception in first trimester abortion.
To determine the second-trimester amniotic fluid concentrations of complement split products in pregnancies subsequently affected by early-onset preeclampsia.
Consequently, the present study aimed to determine the second-trimester amniotic fluid concentrations of complement split products Bb, C4a, C3a, and C5a in pregnancies subsequently affected by early-onset preeclampsia compared to control uncomplicated pregnancies.
To investigate the use of operative hysteroscopy instead of traditional curettage in women with retained products of conception (RPOC) following first trimester medical abortion, with the aim of reducing post-operative intrauterine adhesions.
The purpose of this study was to compare clinical outcomes of conservative management versus surgical evacuation of retained products of gestation after misoprostol treatment for first trimester spontaneous miscarriage using less restrictive transvaginal ultrasound criteria for diagnosing "empty uterus," which were managed conservatively.
A retrospective audit of second-trimester procedures at one facility in New Zealand found that evacuation for retained products of conception was significantly more common among women undergoing medical induction [ 4].
d Non-pharmacological methods used in the 1st trimester of pregnancy included lifestyle and dietary changes, and the use of ginger, acupressure, homeopathic products, herbal teas, mint or lemon.
