HbA1c levels were also assessed in each trimester, using high-performance liquid chromatography (Bio-Rad, Strasbourg, France).
Further models were built narrowing the SBV infection period by splitting the above semesters in trimesters as to assess variations in herds' performance relative to the reference trimester Oct-Dec 2011. Oct-Dec 2011
Results: Despite an excellent performance of second trimester MSS at a maternal age ≥35 years (94.4% detection rate (DR) of trisomy 21 at a false positive rate (FPR) of 22.4%), the proportion of patients above 35 years of age in the study population was significantly lower than in the Flemish general pregnant population (5.5% versus 8.9%, P<0.001).
Ab-arrays have therefore considerable potential to help increase the performance in first trimester screening for DS, as well as other pregnancy outcomes.
Finally, a meta-analysis on the performance of first trimester uterine artery Doppler showed similar predictive accuracy for pre-eclampsia and other complications such as stillbirths and abruption (Velauthar et al., 2014).
Our objective was to describe performance of first-trimester combined risk assessment in twin pregnancies.
This study aimed to assess the predictive performance of first-trimester fetal nuchal translucency (NT), ductus venosus (DV) Doppler, and hemoglobin A1c (HbA1c) to predict fetal anomalies in women with pregestational diabetes.
The purpose of this study was to compare the performance of first-trimester nuchal translucency (NT) cutoff of ≥3.5 mm with NT percentiles that were calculated for crown-rump length to identify fetuses with critical congenital heart defects (CCHDs).
Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis.
The investigators concluded that the performance of first-trimester screening for early SGA was strongly influenced by concomitant preeclampsia.
