Sentence examples for trim associated from inspiring English sources

The untagged αβTCR from Jurkat cells did not bind to NP-sepharose and thus TRIM was not detected (lane 2); however, both TRIM and ζ were purified from scTCR lysates,, indicating that TRIM associated to the scTCR.

This comprehensive review of TRIM and TRIM-like associated C-terminal domains confirmed that a discrete number of motifs have been selected downstream of the tripartite motif in humans.

Indeed, on May 31 Polaroid executives told analysts and reporters that it would trim costs associated with its instant photography business, and milk it for cash to pay down debt and finance its own digital technologies.

TRIM is associated with some, but not all T cell receptor complexes and plays a role in thymic selection [ 44, 45].

To test whether TRIM is associated with the scαβTCR, we lysed 31.13scTCRβ or Jurkat cells in digitonin and affinity-purified αβTCR complexes with NP-sepharose.

For example, the density of distinct spines in the hippocampus increases 24 h after eye-blink conditioning (Leuner et al. 2003), and in vivo imaging of spines in the whisker barrel model suggests that the change in somatotopic representation induced by whisker-trimming is associated with stabilization of a subset of new spines over a period of days (Holtmaat et al. 2006).

Since the γδTCR also contains ζ, we tested whether TRIM might associate with the γδTCR and thereby give rise to a second larger detectable γδTCR.

The observation that TRIM is easily lost from the αβTCR complex shows that TRIM is loosely associated and that a large percentage of αβTCRs might contain TRIM in the living cell.

We identified three sites exhibiting signatures of positive selection in TRIM31; two of these sites are in the C-terminal region, which is not homologous to any known TRIM-associated domains but may represent an analogous virus-interacting domain (fig. 1).

CD3 subunits are then degraded in lysosomes, however, TRIM is not subject to this trafficking route and remains intact; 4. TRIM is also associated with the γδTCR.

Unexpectedly, the closest counterparts of finTRIM B30.2 sequences were not found in other TRIM, but were associated with NACHT and leucine-rich repeats (LRRs -ribonuclease inhibitor (RI)-LRRs -ribonuclease proteinhibitor