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In Caenorhabditis elegans, the introduction of double-stranded RNA triggers sequence-specific genetic interference (RNAi) that is transmitted to offspring.
Delivery of siRNA into the cytoplasm of cancerous cells where it triggers sequence-specific mRNA degradation has recently emerged as a powerful tool in gene therapy.
Fig. 8 The RS trigger sequence diagram.
Then the trigger sequence initiated strand displacement amplification reaction to produce numerous G-quadruplex forming sequences.
A single-stranded DNA (ssDNA) probe with two uracil bases and a trigger sequence were designed.
Firstly, bleomycin cleaved bicyclo-hairpin probe to release a trigger sequence.
Subsequently, the trigger sequence was annealed with the reporter probe, initiating the polymerization and nicking amplification reaction.
If the triggered event in western Shikoku is related to the NVT, P-wave triggering is the beginning of the triggering sequence of NVT.
It has been proposed that a "consensus trigger sequence" exists that is necessary within the coiled-coil domains of various proteins to trigger folding.
Although the substitutions did not bring the overall sequence in closer agreement to the consensus trigger sequence, they increased coiled-coil folding and stability.
In this strategy, a bicyclo-hairpin probe was ingeniously designed for bleomycin detection, which could silence the trigger sequence to reduce non-specific hybridization of detection method.
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