The phosphatidylinositol-3,4,5-triphosphate lipids trigger the attachment of Akt to the plasma membrane, where it subsequently becomes phosphorylated at two key sites, threonine 308 and serine 473, resulting in its full activation.
It's part of the attachment.
"We're banning the use of the attachment".
In fact, attachment research has shown that our attachment style with our own parents is the biggest predictor of the attachment style we'll have with our child.
The universal attachment should have a rubber band around the narrow end of the attachment.
This comparatively fast response was in contrast to the general 12 24 h required for attachment and metamorphosis in response to live CCA [20], [30] and suggested that the trigger of larval attachment is either separate from metamorphosis per se, or is bypassed [33].
On the one hand, sources of reward trigger heightened distress when the attachment object is being threatened.
However, DR5 is involved in mediating anoikis, a form of apoptosis triggered by loss of attachment of cells from the extracellular matrix [36], [37].
Their downregulation could disrupt the G2-M checkpoint control, the assembly of kinetochore, and the attachment of mitotic spindle microtubules to sister chromatids, thereby triggering mitotic catastrophe.
Activation also triggers the release of storage granules and increased exposure of GP IIb/IIIa, furthering the attachment of additional platelets.
