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Moreover, activation of RLR signaling by cytosolic dsRNA triggers marked apoptotic response independently of INF- β.
First, systemic hypoxia triggers marked release of ATP from the ventral medullary regions located within and in a close proximity to the RVLM [ 16].
The plant hormone ethylene plays a key regulatory role in climacteric fruit ripening, which triggers marked changes in fruit flesh color, texture, flavor, and aroma [ 1]. 1-Methylcyclopropene (1-MCP), a receptor-binding antagonist of ethylene, blocks the effects of ethylene and is used commercially to slow fruit ripening [ 31, 32].
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On the other hand, when CD44+ cells were transplanted from the in vitro to in vivo environment triggering marked cell loss through apoptosis, a 100 fold reduction of tumor cells was able to initiate tumors at a faster rate in sequential mice generations, demonstrating the robustness of the stem cell-like subpopulation contained in the selected cells.
In the present case chronic hypoxemia obviously triggered marked erythrocytosis without improving blood oxygenation.
After postnatal day 10, subcutaneously-injected EGF and neuregulin-1 failed to trigger marked ErbB phosphorylation in the brain [ 38].
In human coronary smooth muscle cells (HCSMC), pretreatment with Res 1-1000 μM) triggered marked inhibition of endothelin-1-evoked cell proliferandon and ERK1/2 activation [ 33].
An electronic flashlight signal synchronized with an electronic trigger marked simultaneously the video and EMG recordings, respectively, to synchronize EMG and video recordings.
Low 4OHT doses led to no (0.05 mg) or a small (0.1 mg) increase in IFE thickness, whereas medium and high doses triggered marked thickening (Fig 2B D, F H, J).
In support of these findings, a recent study reported that activation of the TLR4/NF-κB pathway in microvascular ECs triggered marked upregulation of inflammatory molecules, which play a major role in the cross talk between ECs and monocytes/macrophages, leading to upregulated MMP expression, mainly via IL-6 secretion (Lu et al., 2012).
These triggers are marked in the text and consequently linked to a set of gene or protein names to define the full event.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com