Clustering of immunoreceptors upon association with multivalent ligands triggers important responses including phagocytosis, secretion of cytokines, and production of immunoglobulins.
This indicates that these cells upon stimulation would have an increased capacity to respond to innate immune triggers important in COPD pathogenesis.
The human-to-mosquito transmission triggers important molecular changes in the gametocytes, which initiate gametogenesis and prepare the parasite for life-cycle progression in the insect vector.
The consequence of the apoptotic process is the so-called arterial denudation, which triggers important proatherosclerotic processes such as smooth muscle cell proliferation, migration, and matrix secretion.
Pentamidine, another drug currently used for leishmaniasis treatment, is highly toxic and triggers important adverse effects, such as diabetes mellitus, severe hypoglycemia, hypotension, myocarditis, and renal toxicity and can ultimately cause death [ 1, 24].
While culturing MSCs, it was shown that oxygen condition, availability of cytokines and growth factors supplements in the culture media triggers important factors which are helpful in the homing of MSCs.
