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Expression of Ets1 in the basal layer of the skin of K5-Ets1 BT mice triggers alterations in the Notch signaling pathways, which are not significantly altered in Inv-Ets1 mice.
The upregulation of these pathways, however, triggers alterations in protein homeostasis, muscle atrophy and cell death.
It is generally assumed that plants perceive AM fungi even before physical contact between the two symbionts, and that recognition of Myc factors triggers alterations in Ca2+ levels and transcriptional responses in host roots [ 7, 9, 11, 41].
The decreased expression of neuronal structure proteins complements previous data, which show that chronic mild stress triggers alterations of hippocampal synapses and promotes a decrease in dendritic spine density [ 7].
Under conditions typical of transient assays (OD600 = 0.8, microscopy 2 3 days post-infiltration) we confirmed the previously reported stromule induction by GV3101 (pMP90) (GV) and found that GV triggers alterations to plastid position and starch accumulation.
injections of infliximab rescued glucose tolerance in APP/PS1 mice, establishing that brain inflammation triggers alterations in peripheral glucose homeostasis in AβO-injected mice and in the APP/PS1 mouse model of AD.
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TLR9 engagement triggers alteration of the cellular redox balance, tyrosine phosphorylation of vav1 by a src-related tyrosine kinase [39], and the induction of cell signaling pathways including mitogen-activated protein kinases (MAPKs) and NFκB [37].
For example, the RNAP II activity that triggers alteration of the chromatin state of previously repressed promoters - could be accompanied by lower Spt6 activity.
To determine whether oxidative stress triggers alteration of the intracellular mitochondrial network in ONH astrocytes and whether CoQ10 treatment inhibits this alteration in mitochondria against oxidative stress, the mitochondrial morphology of ONH astrocytes were assessed by MitoTracker Red (Invitrogen-Molecular Probes, Eugene, OR, USA) staining, a marker for mitochondria.
We have shown that inflammation in EAE triggers alteration of pre- and post-synaptic sites of glutamate synapses, an effect that could be attributed to activated microglia, as the effect of exposure of striatal slices from control mice to microglia activated by pro-inflammatory cytokines mimicked the alterations of glutamate transmission seen in EAE [ 9].
These changes trigger alterations in the activities of regulated enzymes, leading in turn to increased starch synthesis.
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