Sentence examples for triggers aggregation from inspiring English sources

They reported that nucleozin, a small molecule compound that triggers aggregation and inhibits the nuclear accumulation of NP, can inhibit the replication of influenza virus at a nanomolar median effective concentration (EC50) (Kao et al., 2010).

Moreover, we have shown that DOPAL is toxic to neurons at physiological concentrations in vitro [19], [21] and also triggers aggregation of α-synuclein [21].

We have shown previously that DOPAL is toxic to PC12 cells in vitro at dosages as low as 6.6 µM [19] and triggers aggregation of α-synuclein in vitro at dosages as low as 1.5 µM [21].

It is argued this triggers aggregation of Aβ [ 17].

Together, these findings demonstrate a novel molecular mechanism that triggers aggregation and toxicity of Aβ.

However, when nitrated protein is added to unmodified α-synuclein, it triggers aggregation and amyloid formation, even at substoichiometric concentrations.

A series of recent studies has shown, however, that when aggregates were injected into the brains of recipient animals, they triggered aggregation of the cognate soluble protein in the host [ 1].

Protein misfolding can be deleterious by triggering aggregation and insolubilization.

To trigger aggregation, ctDNA, λDNA or pBR322 DNA at given doses was added into the mixtures.

So, in the presence of a reduced amount of DJ-1 TAT-α-syn aggregation can start at a nanomolar scale that is normally protective and too low to trigger aggregation by itself.

Thus, in addition to the shorter Mca1432 version, theoretically also the longer Mca1 version could be expressed by their construct, perhaps at a level that could not be detected under their assay conditions but sufficient to trigger aggregation of Mca1.