Sentence examples for triggering terminal from inspiring English sources

If so, the wild-type alleles of these genes may suppress cell proliferation by triggering terminal differentiation.

Through the production of cAMP, activates cAMPdependent protein kinases (PKAs), triggering terminal differential and the production of spores.

Indeed, when we tested pairwise combinations of loss and gain of the two genes, we found phenotypes that were consistent with miR-8 triggering terminal differentiation and MET by repressing escargot (Fig 4A D).

Ahonen C et al. reported TRAF6 played a very important role in triggering terminal B cell differentiation to plasma cells, and the loss of TRAF6 recruitment abrogated the generation of long-lived bone marrow plasma cells that secrete either low- or high-affinity nitrophenol-specific antibodies [ 44].

We further propose the existence of an unidentified factor that is distinct from the CDT, and involved with a reversible DNA fragmentation that does not trigger terminal apoptosis in oral epithelial cells.

As already described, in cultured primary human keratinocytes overexpression of Dll1 does not promote differentiation within the expressing cells (Fl Dll1 in Figure 3) but triggers terminal differentiation of neighbouring cells (non-cell autonomous; [ 15]); indeed Dll1 expression is used as a marker of cultured human epidermal stem cells [ 39 ].

We recently demonstrated that myeloma cells are highly sensitive towards proteasome inhibitors due to their extensive rate of immunoglobulin synthesis, thereby triggering the terminal unfolded protein response (UPR) and apoptosis via endoplasmic reticulum (ER) stress.

According to this model, the destruction of Geminin when cells enter G0 phase would relieve the repression of Brg1 and other transcription proteins and trigger terminal differentiation [4], [13], [14].

On the basis of our findings, PKC η promotes keratinocyte growth arrest and triggers terminal differentiation.

For example, loss of contact with the ECM or reduced integrin expression in adherent cells triggers terminal differentiation of cultured epidermal stem cells [ 84, 85].

Then, template-free DNA extension reaction was triggered by terminal deoxynucleotidyl transferase (TdT), producing amounts of single-stranded DNA (ssDNA).