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But analysts said that parts of the company could help fill gaps in the bigger publishers' lineup without triggering resistance from regulators.
As liquefaction is triggered when the effective stress path crosses the IL, hence liquefaction triggering resistance increases with decreasing specimen size.
Earlier this year, researchers at Harvard Medical School in Boston reported finding the naturally occurring protein, called endostatin, which promised to shrink tumors without triggering resistance (ScienceNOW, 23 January).
In plants, EF-Tu is involved in chaperone activity to protect protein aggregation in response to environmental stress, thereby facilitating degradation of N-terminally blocked proteins by the proteasome and triggering resistance to pathogenic bacteria.
These mechanisms might impair both cytotoxic and cytostatic effects of trastuzumab (reviewed in [ 4]), triggering resistance escape mechanisms through upregulation of other receptor activities or through perturbation of the bone microenvironment [ 25– 27].
It is also known that the PVX coat protein interacts with a factor, the RanGAP2 protein, which may act as a target or decoy for the PVX coat protein and (in plants harbouring the Rx resistance gene) may participate in triggering resistance [ 58- 60].
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The company's new Python V8 Monaco Collector, with eight watch winders, retails for €38,900 ($52,211), a price that can trigger resistance despite the built-in humidor and bar.
But drug legalisation still triggers resistance from many Uruguayans, sometimes in contradiction with their own liberal values.
Read is skeptical of claims that lugdunin may not trigger resistance, because every antibiotic developed so far has run into resistance problems.
Thus, the APIP12-KO line provides another ideal rice line in a different genetic background to validate the function of APIP12 in Piz-t triggered resistance.
The levels could trigger resistance in influenza-infected birds, Singer says, which could theoretically lead to a "second wave" of a slightly different pandemic strain.
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