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Hypoxia and starvation could have induced those ultrastructural changes by triggering initiation of erythrosomal authophagy.
This illustrates its dual role in triggering initiation through formation of CMG, then preventing re-initiation by inhibiting pre-RC reformation.
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One or both of the following triggered initiation of our EGDT protocol: (a) initial systolic blood pressure <90 mmHg, despite a 20mL/kgg intravenous crystalloid fluid challenge; or (b) initial serum lactate level ≥4 mmol/L.
Since hairpin formation is essential to initiate RAN translation, formation of stable RNA G-quadruplexes by the G4C2 repeat might trigger initiation of translation of the expanded repeat sequences (103, 104).
Buck and Kenni Dinesen Peterson of Aarhaus University used computer models to show how resistance to subducting buoyant continental crust can trigger initiation of a new subduction zone.
We show that TERT ci) retains the full activities of wild-type TERT in enhancing keratinocyte proliferation in skin and in activating resting hair follicle stem cells, which triggers initiation of a new hair follicle growth phase and promotes hair synthesis.
Furthermore, an up-regulation of sulfur metabolism is sufficient to trigger initiation of DNA replication in wild type cells.
This route of vegetation formation has been proposed for Staphylococcus aureus, where the bacterium is endocytosed by valve endothelial cells, and can trigger initiation of the coagulation cascade.
A complex regulatory network triggers initiation of seed maturation and corresponding accumulation of storage products.
We have chosen onset of infection-related organ dysfunction since this is a clinical feature that should trigger initiation of primary sepsis care.
The phosphorylated form of eIF-2 is not able to trigger initiation resulting in the inhibition of protein synthesis [ 26- 28].
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