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The classical assay to assess pbNK function is killing of target cells that lack major histocompatibility complex class I molecules (known as HLA in humans) because this rules out any killing from circulating CD8+ cytotoxic T cells that are triggered to kill on recognition of HLA class I molecules.
A tumor-specific immune response, such as the cytotoxic T lymphocyte or NK response, is triggered to kill (and cull) cancer cells during cancer therapy.
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But the defense contends that Mr. Muhammad cannot be put to death under Virginia's so-called triggerman law unless he actually pulled the trigger to kill Mr. Meyers, and no one has testified that they saw him do so.
And the third interpretation is, I think, the most implausible: you go backwards in time, you're about to pull the trigger to kill your parents before you were born, but there's something preventing you from doing it.
If the government believes that Tamerlan pulled the trigger to kill Collier — or if it can't prove that Dzhokhar did — Dzhokhar could still be prosecuted under a conspiracy theory or as a felony-murder accomplice.
Tsarnaev's older brother, Tamerlan, 26, died following a gunfight with police later that night and it was never established which of the pair pulled the trigger to kill Collier.
A month after the killings, Bamber's cousins found a silencer with flecks of blood on it in a cupboard in the farmhouse – this would have ruled out Sheila being the killer because, with the silencer on the rifle, her arms would not have been long enough to reach the trigger to kill herself, and it left Bamber as the only suspect.
The trigger to kill is often the failure of the relationship with the mother, or a dispute over the children if the marriage has already ended.
Accumulating evidences have established that several chemotherapeutic agents trigger autophagy to kill cancer cells.
This protective effect may appear at first surprising, since loss of Ip is likely not an early event in the molecular cascade triggered by mHtt to kill neurons.
My stance was all wrong, and in any case I would never pull the trigger — not to kill an intruder, not to kill a bird.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com