Since MAP persists within macrophages and it is also processed by dendritic cells, further studies are necessary to evaluate if mutant forms of SLC11A1 alter the processing or presentation of MAP antigens triggering thereby an autoimmune response in T1DM patients.
Furthermore, the latest generation intensive care unit (ICU) ventilators are equipped with very sensitive mechanisms, in terms of both the inspiratory effort required and initial delay, triggering thereby adding little to the overall work of breathing [ 19].
First, ubiquitous HLA-I expression is induced on essentially all myofibers by unknown, possibly infectious or inflammatory, proximal triggers, thereby providing a necessary precondition for antigen recognition by CD8+ T cells.
The experimental results showed that the drainage pool effectively decreased the maximum depth of the flow in the triggering area, thereby avoiding the occurrence of debris flow.
In beta cells, the mitochondria are involved in triggering apoptosis, thereby contributing to the regulation of beta cell mass [19], [20].
It is also possible that multiple TCR could interact sequentially with pMHC molecules (serial triggering model), thereby increasing T cell sensitivity [ 7].
Paleolithic stone weapons made hunting possible and thereby triggered the emergence of permanent top-down command structures.
On that occasion she rocked up without her spectacles, shouted "Oh shit, my glasses!" and thereby triggered the telecast's seven-second time delay (the broadcaster's equivalent of the red button, or the ejector seat).
Overexpression of SOD mutants inhibited ERAD and thereby triggered ER stress with the activation of the IRE1-TRAF2-ASK1 pathway [ 59].
The elevated Cai in IR myocardium may enhance triggered activity [ 3], thereby contributing to IR arrhythmias [ 4].
