Hers is a funny and deeply involving story but its sharp stabs against the women-hatred of the Iranian governing classes are enough to trigger rage.
Perceived threats, real or imagined, can trigger rage.
Taylor has a rare condition known as misophonia, a neurological "glitch" where certain everyday sounds can trigger rage responses, suicidal impulses, and other intense reactions.
The high resolution structure of a S100B octamer has recently been reported and tetramers were proposed to trigger RAGE activation by receptor dimerization.
As already described, these conditions favor formation of 'advanced glycation endproducts', which can trigger RAGE and subsequently lead to sustained inflammation.
On a deeper level, a doctors' inability to cure can threaten his or her fantasy of omnipotence and provoke a sense of inadequacy, and this can trigger rage or hatred toward the patient [ 19, 29, 50].
RAGE-mediated mechanism plays a role in ischemic myocardial injury through triggering RAGE-dependent cellular activation, inducing oxidative stress, and promoting inflammatory proliferative responses leading to vascular dysfunction [ 7, 8].
Plasma EN-RAGE triggers the RAGE pathway as proinflammatory ligand activating key inflammatory signals such as NF-κB and MAP kinase and stimulates cell adhesion molecules.
It is speculated, that the soluble forms of RAGE might counteract inflammatory reflexes triggered by RAGE ligands such as AGEs, S100 proteins and HMGB1 [ 1].
This triggered more rage among the opposition, however, which revealed itself not as a positive force but as petulant illegality.
