In the second mechanism, only SRL docking triggers an induced fit in the RNA, protein or both to shorten the distance and thereby engage Y47 and H49 catalytically.
In Culex species the binding to Cpm1 is triggered by BinB [4], [7], [8]; then BinA docks to the receptor-bound BinB and triggers toxicity, as reported for several A-B toxins [9].
The exchanges were triggered by the Guardian's "greatest speeches of the 20th century" series, after Mr De Klerk was invited to introduce Nelson Mandela's "speech from the dock" at the Rivonia trial.
In this year's bargaining, management asked for new efficiencies on the dock, the ILWU resisted the demand, and when negotiations stalled, the union began a massive slowdown (ostensibly driven by safety concerns) that triggered a PMA lockout.
They found that a single light stimulus triggers vesicles docked with the active zone membrane to undergo exocytosis within 20 ms. These fusion events are followed within 50 100 ms by the appearance of membrane invaginations much larger than a synaptic vesicle, and lateral to the centre of the fusion site.
Furthermore, interactions between RIM1α and Rab3a (Lonart, 2002; Wang et al., 1997) and synaptotagmin (Coppola et al., 2001) suggest roles in vesicle docking and Ca2+ triggering of exocytosis, respectively.
Unstable ADP binding may destabilize the motor-ADP state, triggering Ncd stalk rotation and C-terminus docking, producing a working stroke of the motor.
You could see triggering an alarm or sleep mode by docking an iWatch in a certain way for overnight charging, for instance, or maintaining an active state for mounting when you're at your desk and working.
The extended conformation also provides a potential docking site for GroES, to trigger the final, 100° domain rotation constituting the "power stroke" that ejects substrate into the folding chamber.
In S. cerevisiae t-SNARE docking triggers Ca2+ release from the vacuolar lumen and the resulting cytosolic Ca2+ wave is thought to elicit vacuolar fusion (Merz and Wickner, 2004; Wickner, 2002).
In order to trigger it, you have to click on the dock icon or the menu bar icon.
