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Cracking in thermal barrier coatings (TBC) is triggered by the development of a thermally-grown oxide (TGO) layer that develops during thermal cycling from the oxidation of aluminum present in the bond coat (BC).
Additionally, endochondral ossification process is triggered by the development of osteophytes.
PRCA is triggered by the development of neutralizing antibodies against endogenous erythropoietin that may cross-react with different ESAs [ 7].
So, probably, different patterns of expression triggered by the development of diabetes with a lower level for glypican and a higher level for syndecan, would reflect distinct functions.
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In the case of the bulk material with a sophisticated heterogeneous organization, the crack appears as a result of the development of multiple micro-cracks triggered by the massive breakage of molecular or atomic bonds Fig.
In some populations, male development is triggered by the presence of masculinizing alleles with varying genomic location in some populations, whereas in other populations these factors are fixed and sex is based on the presence of a dominant feminizing allele at another locus [ 5].
This research has been mainly triggered and promoted by the development of potent HDAC inhibitors (HDI) that have already advanced to late phase clinical trials for a broad variety of malignant human neoplasms [ 10, 11].
These findings are consistent with the notion that the formation of endocytic vacuoles is an important early step in the development of cell damage triggered by the inducers of acute pancreatitis.
The formation of these depressions on the dams may be attributed to internal instability caused by suffusion which triggered the development of extensive cracks and soft zones (Fig. 9).
The discovery of product inhibition of ATX by LPA and S1P triggered the development of lipid-based ATX inhibitors (Table 2).
Complex interrelated pathophysiological mechanisms triggered by hyperglycaemia underlie the development of DR. These mechanisms include genetic and epigenetic factors, increased production of free radicals, advanced glycosylation end products, inflammatory factors and vascular endothelial growth factor (VEGF).
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