This is why interaction designer and creative coder Andreas Refsgaard has created Eye Conductor, a music production app that uses facial tracking to translate the human eye's gaze into musical notes or beats in a drum sequencer, while specific facial movements can trigger effects and octave transposition.
Incidentally, there are hints indicating that stress may be a triggering factor in contemporary transposition events of MITEs [ 20].
Thus, bursts of intense transposition, if triggered by particularly drastic environmental stresses, would have been involved mostly in causing the extinction of species rather than in the speciation process.
We did not preselect embryos on the basis of such GFP expression, but used these observations as an indication that a transposition had been triggered.
Indeed, the the transposition of nDart1 can be triggered by ordinary crossing under natural field conditions.
Intermediate situations are also plausible, namely, that the frequency, time line, and downstream consequences of transposition may vary with the triggering event, cell type, tissue, or some other parameter.
In cell culture experiments it is these DSB, and not bona fide transposition, that have been found to trigger premature senescence [ 90].
Pony elements constitute about 1.1% of the genome of Ae. aegypti [ 25], and although their transposition mechanism is still unclear, it could be triggered by unfavorable environmental conditions as was shown for other MITEs in plants for example [ 24, 32, 33].
They are considered to be derived from larger autonomous elements (Feschotte and Mouchès 2000) and probably propagate through a cut-and-paste mechanism of transposition combined with a gap repair and/or aberrant DNA replication, triggered by secondary structures (Izsvák et al. 1999; Coates et al. 2011).
Difference in the copy number may be a result of different transposition rates, but it may also indicate that some elements less efficiently trigger the process of AGR following excision, which would result in a higher frequency of perfect excision.
