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The IgG binds the endogenous insulin receptor or TfR to trigger transport across the BBB and acts as a molecular Trojan horse (MTH) to ferry into brain the fused protein therapeutic.
It was speculated that stimulation of P2X receptors could cause an intracellular acidification, which potentially could trigger transport inhibition.
Combining these adhesive properties with the unique characteristics of nanosized magnetite allowed a noninvasive magnetic signal to trigger transport of compounds out of magnetic nanoparticle-vesicle assemblies.
The similar trends for these parameters suggest membrane perturbation (i.e., "membrane stress") is a clue to the mechanism of grapheme oxide toxicity, in which GO adhesion and internalization processes trigger transport and energetic disorders.
No clear consensus has yet been reached about whether mass transportation systems should be closed during a pandemic; and the mildness of the influenza A/H1N1 pandemic in 2009 (which did not trigger transport closures) offers little prospect of shedding further light on this issue.
Similar(55)
The TfRMAb binds the endogenous TfR on the blood brain barrier (BBB), which triggers transport into brain from blood.
Further, overexpression of HSP70 increases surface levels of MHC class I, and engagement of CD99 triggers transport of MHC I from the Golgi complex to the cell surface along with rearrangement of the actin cytoskeleton.
Hormones are created on an arriving request, are diffused to neighbors and evaporate over time; (2) hormones trigger the transport of corresponding content, which is done hop-by-hop.
The findings imply that storms falling on initially dry recently contaminated soils may trigger contaminant transport and erosion via enhanced surface runoff, and rapid spreading of contaminants once they reach the groundwater systems.
Collectively, our data support a model in which BICD2 allows dynein and dynactin to interact directly on cargoes to trigger long‐distance transport.
The outlook for urban development 2020 and beyond indicates that continued urban sprawl will trigger more transport growth, which together with the higher demand for heating and cooling of housing, will contribute to climate change, as well as regional and local air pollution and noise.
Related(20)
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