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Similar results have been documented for the mTOR inhibitor, rapamycin [5], [6], and the eIF4A modulator, silvestrol [17], and suggests that the tumors derived from the Eμ-Myc model require a DNA damage trigger to undergo apoptosis when translation is inhibited.
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Although the CM exhibits self-renewal, the CM is transient and the entire CM population is triggered to undergo a final round of nephrogenesis at the end of metanephros formation.
If the resultant damage cannot be repaired then cells are triggered to undergo apoptosis.
C. albicans can be triggered to undergo an apoptotic cell death response when exposed to environmental stress such as H2O2, amphotericin B (AmB) or intracellular acidification.
Upon the binding of TNF- α to TNFR1, monocytic cells are triggered to undergo apoptosis.
Perhaps the collapsed micronucleus is triggered to undergo resorption because it is not protected by the conjugation junction.
Monocytes were triggered to undergo apoptosis in response to BH3-mimetic-ABT-737 BH3-mimetic-ABT-737 BH3-mimetic-ABT-737 BH3-mimetic-ABT-737ernatant obtained form resting (RPS) and activated (APS) platelets.
The extrinsic pathway can be triggered to undergo oligomerization when proper ligands bind their respective death receptors, ultimately recruiting adaptor molecules and caspase-8 into a complex resulting in activated caspase-8.
Apoptosis is a complex and active cellular process in which individual cells are triggered to undergo self-destruction in a manner that will neither injure neighbouring cells nor elicit an inflammatory reaction.
Owing to the reversible nature of this inhibition, responding cells are not triggered to undergo apoptosis; it appears likely that MSC to all intents and purposes protect from apoptosis, which is in concordance with the notion that the actual duty of MSC is to support tissue repair.
The authors briefly mention that a reduction in Tjp1a may trigger iridophores to undergo the transition from dense to loose and more migratory behaviors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com