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Time from physiological trigger to activation of a Rapid Response System was a median 0 47 hours (IQR 0 00 to 2 15).
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Supercritical carbon dioxide medium in the near-critical region should be a trigger to the activation of the enzyme by causing the movement of the surface groups and creating an active site, producing stereoselective machinery.
It has been known that lectin is one of the trigger to complement activation [46], [47].
JAK-STAT triggering leads to activation of lineage-specific transcription factors, which results in expression of effector cytokines [ 4].
Population of the second site might be the trigger to initiate IKK activation, possibly through clustering of NEMO.
Another possibility might be that there is an alternative pathway, apart from Ca2+ signalling, that links TCR triggering to NFAT activation.
Some individual TFs can elicit multiple transcriptional responses, while different TFs can be recruited to the same target regions to trigger transcriptional activation leading to cell differentiation [ 33].
Increased levels of intracellular Ca2+ are believed to trigger Cn activation and to be a key regulator of a variety of physiological and pathological processes [10], [14], [15].
Accumulation of misfolded/unfolded proteins is known to trigger activation of PERK, which subsequently phosphorylates eif2a to inhibit protein synthesis.
We investigated the inflammatory response to conidia and hyphae of A. fumigatus and specifically, their capacity to trigger activation of an inflammasome.
RhoH contains a novel ITAM-like motif that serves as a binding site for Zap70, which is then shuttled to the T-cell receptor complex where it serves as a crucial molecule to trigger activation of the LAT signalosome.
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