Sentence examples for trigger terminal from inspiring English sources

We further propose the existence of an unidentified factor that is distinct from the CDT, and involved with a reversible DNA fragmentation that does not trigger terminal apoptosis in oral epithelial cells.

According to this model, the destruction of Geminin when cells enter G0 phase would relieve the repression of Brg1 and other transcription proteins and trigger terminal differentiation [4], [13], [14].

On the basis of our findings, PKC η promotes keratinocyte growth arrest and triggers terminal differentiation.

If so, the wild-type alleles of these genes may suppress cell proliferation by triggering terminal differentiation.

Through the production of cAMP, activates cAMPdependent protein kinases (PKAs), triggering terminal differential and the production of spores.

For example, loss of contact with the ECM or reduced integrin expression in adherent cells triggers terminal differentiation of cultured epidermal stem cells [ 84, 85].

Indeed, when we tested pairwise combinations of loss and gain of the two genes, we found phenotypes that were consistent with miR-8 triggering terminal differentiation and MET by repressing escargot (Fig 4A D).

Ahonen C et al. reported TRAF6 played a very important role in triggering terminal B cell differentiation to plasma cells, and the loss of TRAF6 recruitment abrogated the generation of long-lived bone marrow plasma cells that secrete either low- or high-affinity nitrophenol-specific antibodies [ 44].

As already described, in cultured primary human keratinocytes overexpression of Dll1 does not promote differentiation within the expressing cells (Fl Dll1 in Figure 3) but triggers terminal differentiation of neighbouring cells (non-cell autonomous; [ 15]); indeed Dll1 expression is used as a marker of cultured human epidermal stem cells [ 39 ].

Levels of Jagged-1 and Notch increased during the differentiation process, and may trigger keratinocyte terminal differentiation and cornification [24].

Activation of iDCs trigger their terminal differentiation program, namely maturation, which includes the switch from an antigen capture to a T-cell sensitizing mode, and the migration of activated cells, via-lymphatic vessels, to T-cells rich areas of regional draining lymphonodes.