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The study provides novel insights into the underlying mechanisms that trigger progression into hypoxemia, facilitating new hypotheses and treatment options.
Our data shows that even acute exposure to SHS in utero causes proteostasis/autophagy impairment in the pediatric/neonate murine lungs as a plausible mechanism to trigger progression of chronic lung disease(s).
Given the evolutionary conservation of basic biological mechanisms, one would anticipate that hCdc14B, like yCdc14, controls processes that trigger progression through mitosis.
We demonstrated that RPE dysfunction might lead to dysregulation of macrophage clearance function and angiogenic homeostasis as a result of oxidative damage which may trigger progression towards CNV in smoker patients with dry AMD.
Both complexes trigger progression of the G1 phase and entry into the S phase.
The processes that characterize and trigger progression of preinvasive ductal carcinoma in situ (DCIS) to invasive breast cancer remain elusive.
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It is a useful marker for medical professionals: it allows categorisation, it triggers progression through the system, and it dictates best practice for different stages of treatment.
Thus, it follows that the genetics of dyslipidemia, obesity, and nonalcoholic fatty liver disease are central in triggering progression of the syndrome to overt expression of disease traits and have become a key focus of interest for early detection and for designing prevention and treatments.
Fertilization activates the anaphase-promoting complex/cyclosome (APC/C), triggering progression past anaphase I [ 3].
If so, the parasites should have become sensitive to the differentiation trigger cis-aconitate, the chemical cue that triggers progression from the stumpy to the procyclic insect stage.
Thus, one could predict that additional events are required to trigger cancerous progression.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com