DNA breaks triggered mobilization of the slow BRCA2 population, making it available for interaction with Rad51, as determined by simultaneously measuring FCS curves for both proteins using two distinct fluorophores.
In this regard, TR-mediated responses trigger the mobilization of DOR from the PML bodies.
Oxidative stress can trigger the mobilization of Ca2+ into cytosol, where endoplasmic reticulum is the important Ca2+ storage [ 24].
For example, MTs present an 82 kDa surface glycoprotein (GP-82) that is implicated in parasite internalization but does not trigger actin mobilization to invasion sites [ 80, 81].
In a heterologous bioassay, this peptide was able to trigger a mobilization of lipid reserves when injected into the green shield bug Nezara viridula whereas it did not provoke pigment migration when injected into the shrimp Palaemon pacificus [ 42].
After their release into the BM environment, these proteases may inactivate a number of proteins essential for retaining HSPCs within the BM, that is, vascular cell adhesion molecule-1 VCAM-1/CD106 VCAM-1/CD106Xchemokine1 and its CXCR4 receptor (in humand), and c-KitsreCXCR4receptorf whinhumanstrigger HSPC mobilizandon [ 41, 42].
Physiological fluctuations of unfolded protein levels may cause temporary up-regulation of protein-folding machinery, while a prolonged or excessive incorrectly folded protein load can trigger full mobilization of mechanisms for the normalization of cell function and prevention of cell death.
This is consistent with a model for regulation of HA in which the Ca2+ stored at the sperm neck is pivotal to HA induction and CatSper-mediated Ca2+ influx in the flagellum acts as a trigger for mobilization of this store (Alasmari et al., 2013a, b).
Oxyhydroxide reduction mechanism driven by microbial activity degrades the arsenate to arsenite and triggers the mobilization.
They are crucial in triggering the mobilization and migration of immunocompetent cells such as monocytes, neutrophils, lymphocytes, and dendritic cells along the bone marrow sinusoids that frequently anastomose with capillaries and in directing them into the inflamed tissues [22].
