Physiopathological mechanisms that trigger clinical manifestations in pre-eclampsia (PE) remain unclear, and management is still a challenge.
It should be noted, however, that the models employed by Ruth and colleagues and Gan and colleagues are different from the model originally described by Xiao and colleagues [ 19] because a subnephritogenic dose of heterologous anti-GBM antibodies is used to trigger disease manifestations.
Third, diagnostic triggers are manifestations that prompt suspicion of MFS in formerly undiagnosed subjects.
Whether these or other mechanisms, besides lack of ADAMTS-13 activity, play a role in triggering clinical manifestations of TTP remains to be determined.
Acute thrombotic complications such as atherothrombosis can result in vessel occlusion and the restriction in blood flow may trigger the manifestation of disease, heart attacks.
On one hand, IBD patients are more susceptible to enteric pathogens [ 13, 45, 46], while on the other hand, recurrent episodes of acute bacterial enterocolitis trigger the manifestation of IBD in susceptible individuals [ 11, 12, 47].
Fourth, prognostic triggers are manifestations such as aortic dilatation or mitral valve prolapse that, fifth, may give rise to complications such as aortic dissection or mitral valve regurgitation (Table 2).
We speculate that SIGBIC, when it overcomes the fibrous capsule, may determine a systemic autoimmune reaction that triggers a manifestation similar to anaplastic large cell lymphoma.
The disease broke out long after removing the birds from the one-month quarantine and the stress of the laying period was probably the factor triggering clinical manifestation.
Sunlight and other ultraviolet light can trigger the skin manifestations.
