Sentence examples for trigger loss from inspiring English sources

Importantly, the results suggest that over-oxidation may trigger loss of functions due to local structural modification in the Cys106 containing pocket of DJ-1 and structurally destabilize the dimeric state of DJ-1, which is believed to be its bioactive conformation.

Taken together, the results suggest that preferences of USP7 for specific PML isoforms underlies its ability to trigger loss of PML-NBs and proteins.

Microscopy images of H1299 and Saos2 cells (also p53-negative) after overexpression of USP7 or the C223S mutant also confirmed that USP7 can trigger loss of PML NBs in the absence of p53 and that the effect is independent of ubiquitin cleavage by USP7 (Figure S2).

They identify particularly useful strategies such as self-monitoring, identification of high risk situations and coping skills to manage emotions or situations which may trigger loss of control.

For example, the juxtaposition of a lightly methylated NOR with a more heavily methylated NOR could trigger loss or gain of DNA methylation from the rRNA gene arrays.

Any abnormal proteinuria may not only trigger loss of kidney function, it also represents a considerable risk for renal disease and cardiovascular morbidities.

If they fall, or if industry losses are so steep that they trigger losses in the sidecars, they will lose some of their luster as investment opportunities.

Both of them triggering loss of pathogen control and inducing aberrant clinical consequences.

We conclude from these experiments that FasL is required for the TNFα triggered loss of RGCs.

Unilateral expression of TDP-43WT in postmitotic motor neurons for 6 days triggered loss of roughly 30% Isl1/2+ spinal motor neurons relative to the untransfected control hemicord (Fig. 5B).

Acadesine triggered loss of cell metabolism in K562, LAMA-84 and JURL-MK1 and was also effective in killing imatinib-resistant K562 cells and Ba/F3 cells carrying the T315I-BCR-ABL mutation.